Chair of Biochemistry and Molecular Biology

Welcome to our Department

Our research focuses on the control of cell growth and proliferation and its deregulation in human tumors.

We study transcription factors such as Myc and SREBP proteins that control gene expression programs involved in central biological processes such as cell cycle progression, apoptosis, protein translation and metabolism.

Our work aims to understand how these factors work and how they are regulated and to use this knowledge for novel strategies for tumor therapy.

The department is part of the
Comprehensive Cancer Center Mainfranken.

Event Announcements

CCC Seminarreihe

Decoding and Exploiting Aberrant Transcription Leukemia
Referent: Johannes Zuber, IMP Research Institute of Molecular Pathology, Wien
Ort: Biozentrum Universität Würzburg, Hörsaal A 102
23. November 2017 17:00 c.t.
Organisator: GSLS - CCC - FOR 2314 Seminarreihe

mRNA cap regulation in Embryonic Stem Cell and T Cell fate
Referent: Victoria Cowling, School of Life Science, University of Dundee
Ort: Biozentrum Universität Würzburg, Hörsaal A 102
14. Dezember 2017 17:00 c.t.
Organisator: GSLS - CCC - FOR 2314 Seminarreihe

New Publications

Jennifer M. Gerlach, Michael Furrer, Maria Gallant, Dirk Birkel, Apoorva Baluapuri, Elmar Wolf, and Peter Gallant (2017) PAF1 complex component Leo1 helps recruit Drosophila Myc to promoters, PNAS, doi: 10.1073/pnas.1705816114

Klein-Hessling, S., Muhammad, K., Klein, M., Pusch, T., Rudolf, R., Floter, J., Qureischi, M., Beilhack, A., Vaeth, M., Kummerow, C., Backes, C., Schoppmeyer, R., Hahn, U., Hoth, M., Bopp, T., Berberich-Siebelt, F., Patra, A., Avots, A., Muller, N., Schulze, A. & Serfling, E. (2017) NFATc1 controls the cytotoxicity of CD8+ T cells, Nature Communication 8, 511.

Dejure, F.R., Royla, N., Herold, S., Kalb, J., Walz, S., Ade, C.P., Mastrobuoni, G., Vanselow, J., Schlosser, A., Wolf, E., Kempa, S., and Eilers, M. (2017) The 3’-UTR of MYC couples RNA polymerase II function to ribonucleotide levels. EMBO J, Apr 13 doi:10.15252/embj.201796662. [Epub ahead of print]

Ros, S., Flöter, J., Kaymak, I., Da Costa, C., Houddane, A., Dubuis, S., Griffiths, B., Mitter, R., Walz, S., Blake, S., Behrens, A., Brindle, KM., Zamboni, N., Rider, M.H. and Schulze, A., (2017) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells, Oncogene, doi: 10.1038/onc.2016.477

Open Positions

If you are interested in working with us, please contact our administrative assistant, Rosemarie Roeder, or contact the person you would like to work with directly.

Prof. Dr. Martin Eilers

Dr. Markus E. Diefenbacher

Dr. Peter Gallant

Prof. Dr. Almut Schulze

PD Dr. Armin Wiegering

Dr. Elmar Wolf -> Open Positions

Kontakt

Lehrstuhl für Biochemie und Molekularbiologie
Am Hubland
97074 Würzburg

Tel.: +49 931 31-84112
E-Mail

Suche Ansprechpartner

Hubland Süd, Geb. B1 Hubland Nord, Geb. 32 Julius-von-Sachs-Platz 2 Fabrikschleichach Hubland Süd, Geb. B2 Campus Medizin