Chair of Biochemistry and Molecular Biology

Welcome to our Department

Our research focuses on the control of cell growth and proliferation and its deregulation in human tumors.

We study transcription factors such as Myc and SREBP proteins that control gene expression programs involved in central biological processes such as cell cycle progression, apoptosis, protein translation and metabolism.

Our work aims to understand how these factors work and how they are regulated and to use this knowledge for novel strategies for tumor therapy.

The department is part of the
Comprehensive Cancer Center Mainfranken.

Event Announcements

CCC Seminarreihe

Cancer Cellular Metabolism at a Spatio-Temporal Resolution
Referent: Tomer Shlomi, Israel Institute of Technology, Haifa
Ort: Biozentrum Universität Würzburg, Hörsaal A 101
18. September 2017 11:00 c.t.
Organisator: GSLS - CCC - FOR 2314 Seminarreihe

A Senescene-disabling H3K9 Demetylase Switch in Melanoma
Referent: Clemens Schmitt, Charité Universitätsmedizin Molekulares Krebsforschungszentrum (MKFZ), Berlin
Ort: Biozentrum Universität Würzburg, Hörsaal A 101
18. September 2017 17:00 c.t.
Organisator: GSLS - CCC - FOR 2314 Seminarreihe

Targeting Molecular Vulnerabilities in Cancer
Referent: Martin Sos, Molekulare Pathology, Universitätsklinik, Köln
Ort: Biozentrum Universität Würzburg, Hörsaal A 102
5. Oktober 2017 17:00 c.t.
Organisator: GSLS - CCC - FOR 2314 Seminarreihe

New Publications

Dejure, F.R., Royla, N., Herold, S., Kalb, J., Walz, S., Ade, C.P., Mastrobuoni, G., Vanselow, J., Schlosser, A., Wolf, E., Kempa, S., and Eilers, M. (2017) The 3’-UTR of MYC couples RNA polymerase II function to ribonucleotide levels. EMBO J, Apr 13 doi:10.15252/embj.201796662. [Epub ahead of print]

Ros, S., Flöter, J., Kaymak, I., Da Costa, C., Houddane, A., Dubuis, S., Griffiths, B., Mitter, R., Walz, S., Blake, S., Behrens, A., Brindle, KM., Zamboni, N., Rider, M.H. and Schulze, A., (2017) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells, Oncogene, doi: 10.1038/onc.2016.477

The impact of pulmonary metastasectomy in patients with previously resected colorectal cancer liver metastases.
Wiegering A, Riegel J, Wagner J, Kunzmann V, Baur J, Walles T, Dietz U, Loeb S, Germer CT, Steger U, Klein I.
PLoS One. 2017 Mar 22;12(3):e0173933. doi: 10.1371/journal.pone.0173933. eCollection 2017 Mar 22.

Open Positions

If you are interested in working with us, please contact our administrative assistant, Rosemarie Roeder, or contact the person you would like to work with directly.

Prof. Dr. Martin Eilers

Dr. Markus E. Diefenbacher

Dr. Peter Gallant

Prof. Dr. Almut Schulze

PD Dr. Armin Wiegering

Dr. Elmar Wolf

Kontakt

Lehrstuhl für Biochemie und Molekularbiologie
Am Hubland
97074 Würzburg

Tel.: +49 931 31-84112
E-Mail

Suche Ansprechpartner

Hubland Süd, Geb. B1 Hubland Nord, Geb. 32 Julius-von-Sachs-Platz 2 Fabrikschleichach Hubland Süd, Geb. B2 Campus Medizin